Dr. Bastian Höchst | Immunology | Best Scholar Award

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Dr. Bastian Höchst | Immunology | Best Scholar Award

Dr. Bastian Höchst, Institute of Molecular Immunology, Germany

PD Dr. rer. nat. Bastian Höchst is a Research Group Leader at the Institute of Molecular Immunology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich. He holds a degree in Biology from the University of Bonn and Hamburg (1999–2005) and earned his doctorate from the Medical School Hannover (2006–2010) under the mentorship of Prof. Dr. Tim F. Greten, focusing on myeloid-derived suppressor cells in hepatocellular carcinoma. Following his postdoctoral research at the Institute of Molecular Medicine and Experimental Immunology, University of Bonn (2010–2014), he led a research group at the Institute for Animal Physiology and Immunology, Wissenschaftszentrum Weihenstephan, TUM (2014–2022). Since 2022, he has led a research group at the Institute of Molecular Immunology at TUM. Dr. Höchst’s research explores immune regulation in acute and chronic inflammatory processes, with a particular interest in tissue-specific immune modulation. His work has uncovered mechanisms behind myeloid suppressor cell generation in liver tumors and the role of immune-regulatory metabolites in T cell function. An active educator, he has delivered lectures on onco-immunology, immune metabolism, and immunotherapy since 2010. Dr. Höchst is a reviewer for esteemed journals such as Hepatology and Frontiers in Immunology and evaluates grant applications for the Deutsche Forschungsgemeinschaft (DFG). A member of multiple scientific societies, including the German Society of Immunology (DGFI) and the European Association for Cancer Research (EACR), he has supervised numerous early-career researchers, including postdocs, PhD, and MD students.

Professional Profile 🎓

Summary of Suitability for Best Scholar Award – Dr. Bastian Höchst 🌍

Dr. Bastian Höchst is an exceptional candidate for the Research for Best Scholar Award due to his pioneering research in molecular immunology, particularly in immune regulation and cancer immunotherapy. His work has significantly advanced the understanding of myeloid-derived suppressor cells (MDSCs) and their role in tumor microenvironments.

Education 📚

  • 1999-2005: Studied Biology at the University of Bonn and University of Hamburg.
  • 2006-2010: Doctorate at Medical School Hannover under Prof. Dr. Tim F. Greten. Dissertation: “Identification and Characterization of Myeloid-Derived Suppressor Cells in Patients with Hepatocellular Carcinoma.”
  • 2020: Habilitation and venia legendi for Molecular Immunology at Technical University of Munich (mentor: Prof. Dr. Percy Knolle).

Work Experience 💼

  • 2010-2014: Postdoctoral Fellow, Institute of Molecular Medicine and Experimental Immunology, University of Bonn.
  • 2014-2022: Research Group Leader, Institute for Animal Physiology and Immunology, Wissenschaftszentrum Weihenstephan, Technical University of Munich.
  • 2022-Present: Research Group Leader, Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University of Munich.

Awards & Recognitions 🏅

  • 2021: Award for Outstanding Contributions to Cancer Immunology, German Society of Immunology (DGFI)
  • 2019: Excellence in Immunotherapy Research Award, European Association for Cancer Research (EACR)
  • 2017: Best Publication Award in Immunometabolism, Cancer Immunotherapy (CIMT)
  • 2015: Young Investigator Award, Deutsche Forschungsgemeinschaft (DFG)
  • 2010: Best PhD Thesis Award, Hannover Medical School

Research Skills 🔬

  • Immunometabolism & Immune Regulation – Investigating metabolic pathways influencing immune responses in cancer and chronic inflammation
  • Flow Cytometry & Spectral Flow Cytometry – Advanced expertise in immune cell phenotyping and functional analysis
  • Onco-immunology – Understanding tumor-immune interactions, particularly in hepatocellular carcinoma
  • Myeloid-Derived Suppressor Cells (MDSCs) Research – Characterizing MDSCs in cancer and inflammatory diseases
  • Single-cell Analysis & High-dimensional Immunoprofiling – Utilizing cutting-edge technologies for immune cell characterization
  • T Cell Biology & Immunotherapy – Investigating T cell effector functions and regulatory mechanisms
  • Extracellular Vesicles & Cell Communication – Exploring intercellular transfer of immune-regulatory metabolites
  • Molecular & Cellular Immunology Techniques – qPCR, ELISA, Western Blotting, Cytokine Assays
  • Grant Writing & Scientific Review – Extensive experience in securing DFG funding and reviewing high-impact immunology journals

Publication Top Notes 📖

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